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S100B Antibody, Cat#CAF16202

$279.00

Cat#

CAF16202

Size: 100ug

Quantity:

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Species Reactivity

Human, Mouse, Rat

Host

Rabbit

Clonality

Polyclonal

Application

WB, IHC, ELISA

Estimated Turnaround Time

4-7 business days

Isotype

IgG

Immunogen

A synthesized peptide derived from human S100B

Conjugation

Unconjugated

Specificity

S100B Antibody detects endogenous levels of total S100B

Gene ID

6285

Gene Name

S100B

Swiss-Prot

P04271

Purification

The antiserum was purified by peptide affinity chromatography.

Concentration

1mg/ml

Storage

-20°C

Expiry Date

1 year

Shipping Condition

Ice packs

Comments

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Technical Notes

WB 1:500-1:2000, IHC 1:50-1:200

Restriction

For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

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