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Phospho-p62 Dok (Tyr398) Antibody, Cat#CAF11248

$279.00

Cat#

CAF11248

Size: 100ug

Quantity:

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Species Reactivity

Human, Mouse, Rat

Host

Rabbit

Clonality

Polyclonal

Application

WB, IF/ICC, ELISA

Estimated Turnaround Time

4-7 business days

Isotype

IgG

Immunogen

A synthesized peptide derived from human p62 Dok around the phosphorylation site of Tyrosine 398

Conjugation

Unconjugated

Specificity

Phospho-p62 Dok (Tyr398) Antibody detects endogenous levels of p62 Dok only when phosphorylated at Tyrosine 398

Gene ID

1796

Gene Name

DOK1

Swiss-Prot

Q99704

Purification

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Concentration

1mg/ml

Storage

-20°C

Expiry Date

1 year

Shipping Condition

Ice packs

Comments

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Technical Notes

WB: 1:500-1:2000, IF/ICC: 1:100-1:500

Restriction

For Research Use Only. Not for use in vitro diagnostic procedures, drug use, or for administration to humans or animals.

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