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Recombinant Human UPF0568 protein C14orf166 (C14orf166), Cat#RPC23777

$302.00

Cat#

RPC23777

Quantity:

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Species

Homo sapiens (Human)

Source

E.coli

Tag Info

N-terminal GST-tagged

Biological Activity

Not tested

Estimated Turnaround Time

15-25 business days

Gene Name

C14orf166

Alternative Names

CLE7 homolog

Uniprot

Q9Y224

Expression Region

1-244aa

AA Sequence

MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR

Sequence Info

Full Length

Theoretical MW

55.1 kDa

Purity

>90% as determined by SDS-PAGE.

Storage Buffer

Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level

Not tested

Shipping Condition

Ice packs

Storage

Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Expiry Date

1 year

Research Area

Neuroscience

Restriction

For Research Use Only. Not for use in diagnostic procedures. Not for human or animal drug or food use.

Relevance

RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport

Function

RNA-binding protein involved in modulation of mRNA transcription by Polymerase II

Subcellular location

Nucleus, Cytoplasm, cytosol, Cytoplasm, perinuclear region, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Note=May localize at the centrosome during mitosis (PubMed:15147888), Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264), SUBCELLULAR LOCATION: Nucleus, Cytoplasm

Protein Families

RTRAF family

Tissue Specificity

Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors.

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