3D illustration of antibody molecules on a blue background

Polyclonal Antibody Production Services

Fast, Flexible Custom Polyclonal Antibodies for Research

Selected Citations for Biomatik’s Custom Antibody Services
Polyclonal antibodies (pAbs) remain a powerful and cost-effective tool for research and diagnostic applications. We offer an extensive catalog of polyclonal antibodies, but if you can’t find what you are looking for then Biomatik’s custom polyclonal antibody production service provides high-quality pAbs tailored to your research needs, with flexible host species, express or standard protocols, and optional antigen design and production. Whether you supply your own antigen or choose Biomatik to produce it through our custom peptide synthesis or recombinant protein production services, we deliver purified, validated antibodies with comprehensive project reporting and quality guarantees.

Why Choose Biomatik for Polyclonal Antibody Production

Scientific & Customer Trust: View our selected peer-reviewed citations in Nature, Gastroenterology, and Immunity, alongside our consistent 5-star Google reviews.

Our polyclonal antibody production service typically uses two rabbits – rats, chickens, mice, and guinea pigs are available if required – and is suitable for peptide or protein antigens, which we can design and produce in house, or can be provided by you. Our standard immunization protocol lasts for 70 days, but we can offer an express 42-day protocol if you need your antibody in a rush.

We deliver the affinity-purified antibody, as well as the corresponding antigen protein or peptide if we produced it. Options are also available for modified peptide antigens, including phospho-, formyl-, methyl-, cyclic and acetylated peptides. We offer risk free guarantee for most polyclonal antibody production using peptide or protein antigens from E. coli. No Antibody, No Charge. It is free of charge if we are not able to produce the antibody.

Each project includes:

Free antigen design consultation
Protein or peptide synthesis (if requested)
Immunization
Serum collection and affinity purification (anti-serum can be provided on request)
Final antibodies in PBS/glycerol buffer
ELISA titer report and QA report

Download full details of our polyclonal antibody production packages for details on pricing, service contents and deliverables.

About Custom Polyclonal Antibodies

pAbs provide strong binding, tolerance to antigen variability, and robust performance across a range of applications including ELISA, western blot, and immunohistochemistry. Polyclonal antibody production remains a widely used, reliable, and cost-effective approach for generating high-quality antibodies for research.

Start Your Project Today

Starting your polyclonal antibody project is easy:

Contact our team with your antigen details
Receive a customized quote and project timeline
Approve and initiate production

Request quote

Have any general questions about custom polyclonal antibody production for your research? Contact us, we'll be happy to help you every step of the way.

Polyclonal Antibody Production FAQs

Can you provide information on your packages?

A summary of our packages based on antigen selection is in the table below, or you can download our polyclonal antibody service packages for further information and pricing.

pAb packages with antigen choice	Key deliverables	Quality guarantees
Package #SA0031 Antigen: Protein, supplied by customer Animal: 2 rabbits	15-25 mg protein A/G purified antibody	ELISA >1:256,000; WB positive (for antigen)
Package #SA0050 Antigen: Protein, produced by Biomatik Animal: 2 rabbits	2-5 mg affinity-purified antibody 0.1 mg His-tagged protein (from E. coli), >90 %	ELISA >1:128,000; WB positive (for antigen)
Package #SA0033 Antigen: Peptide, synthesized by Biomatik Animal: 2 rabbits	3-5 mg affinity-purified antibody 5 mg peptide, >85 %	ELISA >1:256,000
Package #SA0035 Antigen: Phospho-peptide, synthesized by Biomatik Animal: 2 rabbits	2-5 mg affinity-purified phospho-antibody 3-5 mg affinity-purified non-phospho-antibody 2-3 mg phospho-peptide, >85 % 5mg non-phospho-peptide, >85 %	ELISA >1:256,000; No cross reactivity on DB

What is the typical turnaround time for custom polyclonal antibody production?
Our typical turnaround time is 3 to 4 months for polyclonal antibody productions. This could vary depending on the antigen type and the antibody package choice you have selected.

I am in a rush to get an antibody for my research. Do you offer an express service for your antibody production?
Our default is a 70-day immunization protocol. However, a 42-day express protocol can be requested for certain packages at no extra cost. Please contact us for more information.

Do we need to provide the antigen?

Our packages include the option for you to supply the antigen yourself, or you can make use of our peptide synthesis and protein production services.

How do I select the appropriate antibody production package for my research?
There are two basic starting antigen types: short peptide sequences or full length proteins. Our antibody packages are designed around these two basic types. The selection may be based on your budget and your downstream applications.

Other factors to consider include:

Signal peptide regions and trans-membrane domains are not suitable for protein antigens, as these regions are generally not available for binding of the resulting antibody. Furthermore, these regions are generally excluded in cases where a recombinant protein is produced for immunization.
The antibodies produced from a short peptide sequence may behave a little differently from one that is produced from a full length protein, although the affinity should be the same. It's the conformational structure from a full protein that will impart this difference, since a chemically-synthesized peptide will be a linear sequence.
If you have a wide range of intended downstream applications – including immunofluorescence, immunohistochemistry, functional assays, WBs, and ELISAs – it may be worthwhile to use the protein antigen approach. If you only need this antibody for WBs or ELISAs, it would be more cost-effective to go with a peptide antigen.

How do I design the appropriate peptide candidate for my custom antibody?
We can perform the antigen design for you at no cost. Simply send us the target sequence or accession #, and our expert team will select the appropriate peptide antigens based on your requirements.

Do you offer other host species for the polyclonal antibody service?
Yes, we do. We have a variety of different hosts you may choose from, including mouse, rat, guinea pig, as well as the standard rabbit. Please contact us for more details.

What is the standard polyclonal antibody production immunization protocol?

Day 0: 1-2 ml pre-immune sera and 1st immunization with CFA
Day 14: 2nd immunization with CFA
Day 28: 3rd immunization with IFA
Day 35: 4th immunization with IFA
Day 42: 5th immunization with NaCl (0.9 %)
Day 49: 6th immunization with NaCl (0.9 %)
Day 56: 7th immunization with NaCl (0.9 %) & serum collected for ELISA testing
Day 63: 8th immunization with NaCl (0.9 %)
Day 70: Final bleed (once serum titer reaches 1:8,000 dilution, proceed with serum collection and purification).

Selected Citations Featuring Biomatik's Custom Antibody Production Services

Custom Protein Expression Services

“We had concerns about hydrophobic proteins with poor solubility. Biomatik started from codon optimization and gene synthesis, and the resulting proteins had significantly improved solubility. In our ELISA assays, they showed high specificity and low background. Excellent quality, fast turnaround, and helpful support—highly recommended.”

Custom Antibody Production Services

“I work on molecular farming, producing recombinant protein in plant suspension cells. I'm completely satisfied after almost 5 years of ordering antibodies at Biomatik. Perfect reproducibility batch after batch, and I hope to continue like this!”

“We are very satisfied with the peptide antibodies you produced. They work exceptionally well for both WB and immunostaining—strong and specific signals. Your pricing, service, and timelines are excellent. I will definitely continue using your service.”

Custom Gene Synthesis Services

“Different groups here have found your service excellent. That’s why another group also decided to go with Biomatik—it came highly recommended.”

“We received the antibody and it works very well! I’m extremely happy with it. We’ll definitely contact you for future antibody projects.”

"I'm very happy with Biomatik, because we have had good results with our protein expression. The service is fast and high quality compared with other companies.”

Custom Peptide Synthesis Services

“I’ve ordered many peptides from Biomatik over the past two years. Every experience has been smooth—thanks to their great customer service and unbeatable prices. I’ll continue choosing Biomatik for all my peptide orders.”

“I’ve used several companies for peptide synthesis, and Biomatik has been the best. Their prices are competitive—half the cost of some others—and the customer service is top-notch. Ordering is quick and pain-free.”

Custom Antibody Production Servicdes

“Biomatik has generated several primary antibodies for me over the past 8 years. All performed beautifully in WB and IH/IF. I’m extremely pleased with their outstanding service, work ethics, and professionalism. Production was always on time and delivered as quoted. I will definitely return for future antibody needs.”

“We ordered polyclonal antibody production using synthetic peptides and received everything on schedule. The antibodies produced strong, specific signals and integrated seamlessly into our experimental protocols. An excellent experience.”

Let customers speak for us

from 218 reviews

We were very pleased with Biomatik’s performance on a custom recombinant protein project earlier this summer. Communication throughout the project was excellent, technical questions were addressed promptly, and the supporting analytical and QC data were clear and comprehensive. The recombinant protein was produced to the requested specifications and delivered on schedule. Based on this experience, we have chosen Biomatik for an additional custom protein production project and would be pleased to work with them again.

Thomas Hatch

08/17/2026

We have been ordering several proteins for our research. Biomatik always delivered very good products, and the service was very reliable. Their customer service has always been very responsive and professional. We are very satisfied with this company.

Davide Z

06/10/2026

A reliable antibody and peptide synthesis company. We’ve been using Biomtik for polyconal antibodies in our research. Turnaround times are consistent, and communication is always clear and professional.

Hsing Yi Cho

02/12/2026

We’ve been using Biomtik for peptide synthesis in our research, and they have proven to be extremely reliable. Turnaround times are consistent, product quality is excellent, and communication is always clear and professional. Highly recommend their services to any lab looking for dependable peptide synthesis.

Tarring Lu

12/02/2025

Biomatik provided excellent support to our Biometrology team at NPL, with timely and reliable protein production services. The quality of the material delivered was to the expected standards, and the communication throughout the project was smooth and efficient.

Andrei Baluna

11/27/2025

We got help from Biomatik for our studies, and the experience was excellent. The customer support team was responsive and knowledgeable, providing detailed documentation and timely updates throughout the process. We appreciate the reliable quality and professional service, and we look forward to working with Biomatik again for further.

Keyao Yu

11/05/2025

I work on molecular farming, producing recombinant protein in plant suspention cells. I'm completely satisfied after almost 5 years ordering antibidies at Biomatik. Perfect reproducibility batch after batch and I hope to continiue like this!

Eduardo Peña

09/03/2025

We have ordered peptides from Biomatik several times. Their quality is excellent and they work with you every step of the way to ensure a quality product.

A G

08/20/2025

Estoy muy satisfecha con los servicios de síntesis de péptidos de Biomatik. Para mí como investigadora, Biomatik cumplió todas mis expectativas técnicas para realizar mi trabajo experimental. Toda su atención es buena!

Cristina Cevallos

05/27/2025

We have purchased peptides from Biomatik for a few years now. Their ordering process was smooth, customer service was responsive and helpful, and the peptides arrived on time and of great quality.

Jeella Acedo

04/23/2025

Great service. I'm a returning customer. The product quality and timeline are both outstanding.

Yue Home Liu

04/21/2025

We have used Biomatik to generate two different antibodies and in both cases they worked extremely well in all the assays we tested, including ELISA, WB, and IFA. I would recommend this company.

Sarah Wootton

03/05/2025

The peptide product is of exceptional quality and is highly recommended for its efficacy.

Haoyang Xin

11/15/2024

I have been using Biomatik's modified peptides for a while and they deliver high quality peptides and a very good technical support

Roi Asor

11/07/2024

I have bought peptides from Biomatic several times and the quality is the best!!!

Kyung Won Park

10/17/2024