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Peptide Synthesis

Peptide Synthesis

 
 

   Custom Peptide Synthesis Service

 
Biomatik has been proudly serving 10,000+ scientists since 2002. To date, we have delivered 52,000+ custom made products to our researchers worldwide. With over 12 years of experience in peptide service, Biomatik is proud to be able to synthesize any peptides in the shortest possible time frame while maintaining a success rate over 99.5%. We are convinced that our custom peptide synthesis service will meet or exceed your expectations. Learn why Biomatik has been trusted by thousands of researchers worldwide – Customer Testimonials and Selected Publications citing Biomatik’s peptide synthesis services. 

   Service Highlights

    • Over 99.5% success rate with "No Peptide, No Charge" policy.
    • Fast turnaround time - most peptides under 30aa are delivered within 2-3 weeks.
    • As low as $3/aa or $80/peptide with best price guarantee.
    • From crude to 99% purity; from milligrams to kilograms.
    • Wide range of peptide modifications are available. See Peptide Modification List.
    • All peptides come with MS and HPLC data. Additional analytical data is available upon request.
 

Peptide Synthesis Deliverables and Pricing

    • Peptide is delivered in lyophilized form.
    • Project QC report, includes HPLC and MS data.

Peptide Purity

5mg (<30aa)

Turnaround Time

Promotional Offer

Crude $3.00/aa ∼2 weeks up to 25% off*
Desalt $4.50/aa ∼2 weeks up to 25% off*
>75% $7.50/aa 2-3 weeks up to 25% off*
>85% $9.87/aa 2-3 weeks up to 25% off*
>90% $11.19/aa 2-3 weeks up to 25% off*
>95% $11.99/aa 2-3 weeks up to 25% off*
>98% $18.08/aa 2-3 weeks up to 25% off*
* Prices may vary depending on the peptide length, complexity and the order volume. Minimum charge $80/peptide.
* Turnaround time is an estimated time only; it does not reflect any production difficulties, if so encountered.
 


 

Peptide Modifications

Last updated: May 18, 2018

N terminus Modification
H (free amine)
Ac (Acetylation)
Fmoc
CBZ
Bz
Bz(4-F)
Bz(4-NO2)
Pyr
D-Pyr
LA-
Mpa-
Mal-b-Ala
Mal-Acp
Aoa

N terminus Fatylation
For (Formylation)
2-Br-Ac
2-Cl-Ac
2-I-Ac
OH-Ac-
But-
Suc
MeOSuc
Iba
Hex-
5-heptenoic acid
5-Hexynoic acid
heptanedioic acid
Oct-
Dec-
Sebacic acid
Lau-
Myr-
Pal-
Ste-
Octanedioic acid
Oleic Acid-

C terminus Modification
-OH (free acid)
-NH2 (Amidation)
Cysteamide, -Cya
-AMC
-OMe
-OEt
-OBzl
-OtBu
-NHMe
-NHEt
-TBzl
p-Nitroanilide

D form normal amino acid
{D-Ala}
{D-Arg}
{D-Asp}
{D-Asn}
{D-Cys}
{D-Glu}
{D-Gln}
{D-His}
{D-Allo-Ile}
{D-Ile}
{D-Leu}
{D-Lys}
{D-Met}
{D-Pro}
{D-Phe}
{D-Ser}
{D-Tyr}
{D-Thr}
{D-Trp}
{D-Val}

Unusual amino acid
{Beta-Asp}
{D-Beta-Asp}
{Gamma-Glu}
{D-Gamma-Glu}
Cys(Cam)
D-Cys(Cam)
{Cys(Acm)}
{Cys(tBu)}
{Met(O)}
{D-Met(O)}
{Met(O)2}
{D-Met(O)2}
{Lys(Ac)}
{Ac-Lys}
{Lys(Dde)}
{Tle}
{D-Ser(octanoic acid)}
2-Thi
3-Thi
{Aib}
{Abu}
{D-Abu}
{Hyp}
{Phg}
{D-Phg}
{Nva}
{D-Nva}
{Norleucine}
{D-Nle}
{Cit}
{D-Cit}
{Orn}
{D-Orn}
{Pen}
{D-Pen}
{Cpg}
{Cha}
{D-Cha}
{Chg}
{D-Chg}
{Dab}
{Dap}
Pra
D-Pra
Allo-Thr
D-Allo-Thr
{D-1-Nal}
{L-1-Nal}
{D-2-Nal}
{L-2-Nal}
{D-2-Pal}
{L-2-Pal}
{D-3-Pal}
{L-3-Pal}
{D-4-Pal}
{L-4-Pal}
{Oic}
{Tic}
{D-Tic}
X (20 kinds amino acids mixture with equal mol)

Fluorescence/Dye labeling
Biotin-
-Lys(Biotin)-
-Lys(Biotin)
Biotin-Ahx-
FITC-
-Lys(FITC)-
-Lys(FITC)
FITC-Ahx-
5-FAM-
5,6-FAM
6'FAM
-Lys(5-FAM)-
Lys(5,6-FAM)
-Lys(5-FAM)
5-FAM-Ahx-
Dansyl-
-Lys(Dansyl)-
-Lys(Dansyl)
Dansyl-Ahx-
5-TAMRA-
5(6)-TAMTA-
-Lys(TAMRA)-
-Lys(5-TAMRA)
{5-TAMRA-Acp}
{Lys(Dnp)}
{D-Lys(Dnp)}
{Dab(Dnp)}
Dap(Dnp)
MCA-
-Lys(MCA)-
-Lys(MCA)
Rhodamine B-
Lys(Rhodamine B)

Phe/Tyr Analogs amino acid
{D-2-Cl-Phe}
{L-2-Cl-Phe}
{D-3-Cl-Phe}
{L-3-Cl-Phe}
{D-4-Cl-Phe}
{L-4-Cl-Phe}
{D-3,4-DiCl-Phe}
{L-3,4-DiCl-Phe}
{D-4-Br-Phe}
{L-4-Br-Phe}
{D-3-F-Phe}
{L-3-F-Phe}
{D-4-F-Phe}
{L-4-F-Phe}
{D-4-NO2-Phe}
{L-4-NO2-Phe}
{D-4-I-Phe}
{L-4-I-Phe}
{D-3-CN-Phe}
{L-3-CN-Phe}
{D-4-CN-Phe}
{L-4-CN-Phe}
{D-2-Me-Phe}
{L-2-Me-Phe}
{D-4-Me-Phe}
{L-4-Me-Phe}
{D-4-NH2-Phe}
{L-4-NH2-Phe}
{D-3-Cl-Tyr}
{L-3-Cl-Tyr}
{D-3,5-DiCl-Tyr}
{L-3,5-DiCl-Tyr}
{D-3,5-DiBr-Tyr}
{L-3,5-DiBr-Tyr}
{D-3-I-Tyr}
{L-3-I-Tyr}
{D-3,5-DiI-Tyr}
{L-3,5-DiI-Tyr}
{D-3-NO2-Tyr}
{L-3-NO2-Tyr}
{D-3,5-DiNO2-Tyr}
{L-3,5-DiNO2-Tyr}
{L-3-F-Tyr}

Homo amino acid
{Har}
{D-Har}
{HomoCit}
{D-HomoCit}
{HomoLeu}
{HomoPro}
{D-HomoPro}
{beta-HomoIle}
{beta-HomoLeu}
{beta-HomoMet}
{beta-HomoPro}
{beta-HomoVal}
Quenched fluorescent peptide
{Abz}
o-Abz- (o-aminobenzoic acid)
{Tyr(3-NO2)}
{Glu(EDANS)}
{DABCYL}
{Lys(DABCYL)}
{Lys(Abz)}
MAPS and Carrier Complex
{Symmetric 2 Branches}
{Symmetric 4 Branches}
{Symmetric 8 Branches}
Lys(Maleimide)
Lys(Mpa)
Lys(Pra)
Lys(Suc)
Lys(glutaryl)
Lys(pGlu)
Lys(For)
Lys(2-Br-Ac)
Lys(Butanoyl)
Lys(Crotonyl)
{Lys(octenyl)}
lys(Ma)
Lys(Pal)
Lys(Oleic Acid)
Lys(Acryl)
Lys(alkine)
Lys(Alloc)
Lys(Aoa)
Lys(cyclopropanecarboxyl)
{Lys(3,5-diiodo-4-hydroxybenzoyl)}
Lys(Methacryl)
Lys(propargyl)
Lys(propionyl)
Lys(Pyruvoyl)
{BSA-Peptide N terminus}
{BSA-peptide C terminus}
{BSA-Peptide via Cys}
{KLH-Peptide N terminus}
{KLH-Peptide C terminus}
{KLH-peptide via Cys}
{OVA-Peptide N terminus}
{OVA-peptide C terminus}
{OVA-peptide via Cys}

Atom Linker
{betaAla}
{Ava}
{Ahx}
{8-Aoc}
{AEA}
{Ado}
{ANP Linker}

Methyl amino acids
{Lys(Me)}
{Lys(Me2)}
{Lys(Me3)}
N-Methyl amino acid
{N-Me-Ala}
{N-Me-Phe}
{N-Me-Leu}
{N-Me-Ile}
{N-Me-Val}
{N-Me-Met}
{N-Me-Nle}
{N-Me-Nva}
{Sar}
{N-Me-Ser}
{N-Me-Tyr}
{N-Me-Thr}
{N-Me-Asp}
{N-Me-Glu}
N-Me-beta-Ala

Cyclic peptide
{Mono Disulfide bridge}
{Double Disulfide bridge}
{Triple Disulfide bridge}
{Random Disulfide bridge}
{Same Seq. Inter-Disulfide bridge }
{Different Inter-Disulfide bridge}
{Amide cyclic (end)}

Phosphorylation
{pSer}
{pTyr}
{pThr}
{D-pSer}
{D-pTyr}
{D-pThr}
{Di-sites in sequence}
{Tri-sites in sequence}

PEG
{Mini-PEG}
{Mini-PEG2}
{Mini-PEG3}
{PEG4}
{PEG-6}
{PEG8}
{PEG-11}
{PEG-12}

Isotope Labeling
H2 (deuterium)
N15
C13
13C15N-K (C-terminal)
13C15N-R (C-terminal)
13C15N-A (C-terminal)
13C15N-I (C-terminal)
13C15N-L (C-terminal)
13C15N-F (C-terminal)
13C15N-P (C-terminal)
13C15N-V (C-terminal)

Stapled Peptides
Single stapled S5 and S5
Single stapled S5 and R8
Single stapled R8 and R8
Double stapled S5 and S5
Double stapled S5 and R8
Double stapled R8 and R8

Misc
FMK, CMK
Insulin Synthesis
N6-Octanoyl
Photocleavable peptides
propargyl-gly
Lys(Myr)
pNA
Lys(N3)




 
 

Additional Peptide Services

Solubility Test (free of charge)
Aliquoting (free for the first 5 tubes)
TFA Removal (switched to acetate or HCl salt, no TFA content guarantee
TFA Removal (switched to acetate or HCl salt, TFA guarantee <1%)
TFA Content Analysis
Acetate Content Analysis (HIPC)
Amino Acid Analysis (AAA, used to determine the relative amino acid composition and free amino acids)
Nitrogen Elemental Analysis (used to determine the desired peptide content)
Microbial Analysis
Endotoxin Analysis
Water Content (Karl Fischer)
MALDI-TOF
NMR
pH Adjustment
Rush Service




 
 

Customer Testimonials of Our Peptide Services

"I have been ordering peptides (both with or without modifications) from Biomatik over and over in the past two years. Every single time the process is extremely smooth - thanks to their great customer service team and production team! Also the prices are just unbeatable. I will definitely choose Biomatik over other companies for all my peptide orders."
- Quoted from Dr. Tam
Optometry, University of California Berkeley
Berkeley, CA, USA.


"Over the years, I have used several companies to synthesize peptides for my research. My experience with Biomatik has been top notch. Biomatik offers quality products at competitive prices. In fact, the latest peptide I ordered from them was about half the cost of several competitors. Their customer service personnel are competent and professional, making the process of ordering peptides quick and pain-free. I will continue to use Biomatik for all my peptide synthesis needs."
- Quoted from Dr. Webb
Department of Cell and Tissue Biology, University of California
San Francisco, CA, USA.


"Our team here is a very satisfied and happy customer.  Your service is prompt and the peptides are working well for us.  We actually ordered a peptide from another company because one of our scientists like to use the same company, and I placed this order with you 2 weeks later than the other one, same quantity just different peptide.  Yours arrived earlier than the other one. We are very impressed. If you ever need any testimonials (which by now I don't think you need any further), just let me know."
- Quoted from Dr. Chen
Vice President, Business Development, Privately Held Biomedical Company
Riverside, CA, USA.


"Easy-to-obtain prompt quotes online, reasonable prices, very responsive service, and high quality peptides. I will continue to use Biomatik and recommend them to colleagues."
- Quoted from Dr. Napper
Head, High-Throughput Screening Drug Discovery Lab, Nemours Center for Childhood Cancer Research
Wilmington, DE, USA


"My boss and I are really glad we synthesized the peptides with you since your dedication and undivided care in our project are apparent. Definitely should we need more peptide synthesis in the future we will be sure to contact you."
- Quoted from Dr. Plummer
M.D. Anderson Cancer Center, University of Texas
Houston, TX, USA


Recent Publications Citing Biomatik's Custom Peptide Service

last updated 2015-11-30

Ahmad, Z., Tayou, J. and Laughlin, T.F. (2015). Asp residues of βDELSEED-motif are required for peptide binding in the Escherichia coli ATP synthase. Int. J. Biol. Macromol. 76, 37-43.

Alhakamy, N.A., Elandaloussi, I., Ghazvini, S., Berkland, C. and Dhar, P. (2015). Effect of lipid headgroup charge and pH on the stability and membrane insertion potential of calcium condensed gene complexes. Langmuir, March 2015 [epub ahead of print].

Hocking, H.G., Hase, F., Madl, T., Zacharias, M., Rief, M. and Zoldak, G. (2015). A compact native 24-residue supersecondary structure derived from the villin headpiece subdomain. Biophys. J. 108(3), 678-686.

Li, F., Yamaki, K., Cheng, Y. and Fang, Y. (2015). Assessment and separation of angiotensin I-converting enzyme inhibitory peptides in Chinese soypaste. Int. J. Food. Engineering Feb 2015 [Epub ahead of print].

Lombardo-Bedran, T.B., Palomari-Spolidorio, D. and Grenier, D. (2015). Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts. Arch. Oral Biol. 60(6), 845-853.

Maximyuk, O., Khmyz, V., Lindskog, C-J., Vukojevic, V., Ivanova, T., Bazov, I., Hauser, K.F., Bakalkin, G. and Krishtal, O. (2015). Plasma membrane poration by opioid neuropeptides: A possible mechanism of pathological signal transduction. Cell Death Dis. 6, e1683.

Trovo, L., Stroobants, S., D’Hooge, R., Ledesma, M.D. and Dotti, C.G. (2015). Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS. Neurobiol. Dis. 73, 319-326.

Schuster, D.J., Metcalf, M.D., Kitto, K.F., Messing, R.O., Fairbanks, C.A. and Wilcox, G.L. (2014). Ligand requirements for involvement of PKCε in synergistic analgesic interactions between spinal μ and δ opioid receptors. Brit. J. Pharmacol. 172(2), 642-653.

Wrobel, J.K., Choi, J.J., Xiao, R., Eum, S.Y., Kwiatkowski, S., Wolff, G., Spangler, L., Power, R.F. and Toberek, M. (2015). Selenoglycoproteins attenuate adhesion of tumor cells to the brain microvascular endothelium via a process involving NF-κB activation. J. Nutr. Biochem. 26(2), 120-129.

Zhai, D., Lee, F.H.F., D’Souza, C., Su, P., Zhang, S., Jia, Z., Zhang, L., Wong, A.H.C. and Liu, F. (2015). Blocking GluR2–GAPDH ameliorates experimental autoimmune encephalomyelitis.  Ann. Clin. Transl. Neuro. Feb 2015 [epub ahead of print].

Last updated 2015-03-23

 

   Have a Question?

      E-mail Biomatik
 

    Why Choose Biomatik?

Biomatik has been proudly serving 10,000+ scientists since 2002. To date, we have delivered 52,000+ custom made products to worldwide researchers. Our team has extensive experience in dealing with standard peptide sequences as well as complex or long peptide sequences. Researchers come to Biomatik not only for our competitive prices, fast turnaround time, but also for our quality, consistency and reputation.
      View Biomatik's Cited Publications at Google Scholar: Click Here

      "I have been ordering peptides (both with or without modifications) from Biomatik over and over in the past two years. Every single time the process is extremely smooth - thanks to their great customer service team and production team! Also the prices are just unbeatable. I will definitely choose Biomatik over other companies for all my peptide orders."
      - Dr. Tam, University of California Berkeley - Optometry, Berkeley, CA, USA

      "Easy-to-obtain prompt quotes online, reasonable prices, very responsive service, and high quality peptides. I will continue to use Biomatik and recommend them to colleagues."
      - Dr. Napper, Nemours Center for Childhood Cancer Research, Wilmington, DE, USA

 

   Ordering Information

 
  
Please obtain an official quote before ordering: Request Quote. Biomatik accepts online, phone, fax and email orders. Please refer to the Quote/Reference number when you place an order - orders are typically confirmed within 24 hours.
    • Order Online: Order Now.
    • By Email: order@biomatik.com
    • By Fax: 1-877-221-3515 (USA/Canada) or 1-519-231-0140 (International).
    • Phone Us: 1-800-836-8089 (USA/Canada) or 1-519-489-7195 (International).

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